HORDB

ID: hor002658
Uniprot ID: Q93745
Protein name: NLP-3
Gene name: nlp-3
Organism: Caenorhabditis elegans
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: AVNPFLDSIG
Length: 10(42-51)
Propeptide: MSKIVACLVLLALSVMCVYSAPYEFRAKRAINPFLDSMGKRAVNPFLDSIGKRSFRPDMITEEKRYFDSLAGQSLGKRSNNRYEMLENYY
Signal peptide: MSKIVACLVLLALSVMCVYS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002658_AF2.pdb

hor002658_ESM.pdb

Mass:	119288	Formula:	C47H73N11O15
Absent amino acids:	CEHKMQRTWY	Common amino acids:	ADFGILNPSV
pI:	3.75	Basic residues:	0
Polar residues:	3	Hydrophobic residues:	5
Hydrophobicity:	73	Boman Index:	85
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	117
Instability Index:	4464	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 17564681
Title: Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry.